Wednesday 13 October 2010

The genetic conditions song (WIP, feedback & suggestions appreciated)

The Genetics 13.10.10 version

(with apologies to Tom Lehrer and Gilbert & Sullivan)

Original: http://www.youtube.com/watch?v=YgFh6IAQoDA


There's cancer and porphyria and hypercalciuria
adrenal hypoplasia, dystrophia myotonica
and hypochondroplasia, 5 Leiden thrombophilia
And hyperoxaluria, methemoglobinemia,
Classic Galactosemia and sickle-cell anemia
ataxia, hemophilia and beta-thalassemia
propionic acidemia hyperphenylalaninemia, (gasp)
and otospondylomegaepiphyseal dysplasia.


There's Cerebral autosomal dominant ateriopathy
with subcortical infarcts and leukoencephalopathy,
And obesity, acrocephaly and compression neuropathy.
And dilated, hypertrophic, and arrhythmogenic right ventricular cardiomyopathy.


Chondrodystrophy and D-glyc'rate dehydrogenase deficiency,
and nonclassic type demyelinogenic leukodystrophy,
hypoxanthine-guanine phosphoribosyl transferase deficiency,
Adrenoleukodystrophy, and just muscular dystrophy.
And Bourneville phakomatosis, perioral Lentiginosis
Tay-Sachs disease and also type 1 neurofibromatosis
Craniofacial Dysostosis, and just plain cystic fibrosis – gasp, gasp, gasp
Dermatosparaxis and Mucopolysaccharidosis


There's cretinism, dwarfism & hyperandrogenism
pantothenate kinase-associated neurod'g'n'ration
colour blindness and idiopathic pulmon'ry hypertension
and fragile X and triple X and XXXXX syndromes.


And these are just the ones that have had write-ups in The Lancet -
So if you're expecting perfect kids I don't fancy your chances....

[This is supposed to come near the end of the show and say 'Hey, we're all genetically screwed up in some way. So let's deal with it and not worry too much.' And also to ensure I'm out of breath by the end.]

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